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Mendelian autosomal recessive inheritance: two germline mutations (one from each parent) to develop the disease, also transmitted by men and women.
Cystic fibrosis is, among people of European descent, the most frequent of the potentially fatal autosomal recessive diseases. In the U.S., approximately 30,000 individuals suffering from CF, the majority are diagnosed within six months of age. Canada has about 3,000 residents with this condition. It is estimated that one in 25 people of European descent health and one of every 29 people Askenazi descent health are carriers of a cystic fibrosis mutation. Although it is less common in these groups, about one in 46 Hispanic nutrients Americans, one in 65 Africans and one in 90 Asians are carriers of at least one abnormal CFTR gene. Argentina is an exception in the context of Latin America, with an incidence of cases much higher than the average for the products region and very close to that registered in the U.S. or Canada, and a prevalence of healthy carriers in the general population is 1 in 30.
Cystic fibrosis was diagnosed in both men and women. For reasons only partially known, life expectancy at birth was greater among males than females affected. One indicator tends to vary largely depending on the scope and quality of care provided by body the health care systems public health. In 1959, wellness the median survival in children with CF was 6 months. For those born in 2006 in the U.S., this value treparia to 36.8 years, according to data compiled by the Cystic Fibrosis Foundation. supplements The life expectancy rate has evolved in a similar way to good the West, except the least developed countries, where they reported significantly lower numbers, in which most of the affected population does not survive beyond the age of ten.
The Cystic Fibrosis Foundation compiles addition, information about the lifestyle of adults with CF. In 2004, the foundation reported that 91 of this population had completed secondary school, and 54 agreed fitness to some form of college education. The data on employment showed that 12.6 of these adults were unable to cardiovascular work (leaving out of the economically active population), and 9.9 were unemployed. On the other hand, marital information said that 59 were unmarried and 36 were married or living with partner. the positive reviews about and what it does for your health and wellness In 2004, 191 women were pregnant with CF in the United States.